Marrone Bio Innovations granted claims for MBI-110 bacterium

Marrone Bio Innovations Inc. has received a notice of allowance from the U.S. Patent and Trademark Office for claims covering MBI-110 bacterium as antifungal and growth promotion composition. MBI previously obtained a patent on the cell broth (which includes the cells, their byproducts and the media used in the fermentation). These additional claims that were allowed include the supernatant and cell fraction (the parts of the fermented bacterial culture containing some anti-fungal and plant health compounds). Together, these claims cover nearly all of the potential commercial embodiments.

The screening platform was directed at finding a solution to challenging diseases. As such, the company tested more than 18,000 microbes against important plant pathogens and discovered the bacterium—also known as the Bacillus strain F727—a new strain of Bacillus amyloliquefaciens with a broad spectrum of performance and standout activity against downy mildews, white moulds and Botrytis grey mould/bunch rots.

MBI-110 is the active ingredient in the two newest products, both biofungicides: Amplitude™ is targeted towards white moulds in potatoes and pulse crops (peas, beans and lentils), soybeans and more. It also controls pathogenic soil fungi, including diseases such as Sclerotinia, Fusarium and Rhizoctonia, as shown in field trials in the U.S., Canada and Europe. Stargus® is focused on downy mildew, Botrytis grey mould and bunch rot in speciality crops such as grapes, as well as leafy greens. The products are proven to improve plant vigour and overall health.

“Growers were in dire need of a new solution for downy mildews, so our scientists set out to find one,” said Founder and CEO Pam Marrone. “Now, these allowed claims grant MBI the strongest possible protection of any and all parts of the MBI-110 microbe. It protects our Amplitude and Stargus products not only for use as a fungicide and to promote plant growth, but also the microbial broth with the bacteria, and anything produced by the microbe.”

MBI holds more than 400 issued and pending patents, and has brought six EPA-registered biological products and one biostimulant to market – more than any other agricultural inputs company in that time.

More information on Amplitude and Stargus is available online at

Leave a Reply

Your email address will not be published. Required fields are marked *